Balancing Thymocyte Adhesion and Motility: A Functional Linkage Between β1 Lntegrins and The Motility Receptor RHAMM
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چکیده
منابع مشابه
Balancing Thymocyte Adhesion and Motility: A Functional Linkage Between β1 Lntegrins and The Motility Receptor RHAMM
Thymocyte differentiation involves several processes that occur in different anatomic sites within the thymus. Therefore, thymocytes must have the ability to respond to signals received from stromal cells and adopt either adhesive or motile behavior. We will discuss our data indicating human thymocytes use alpha4beta1 integrin, alpha5beta1 integrin and RHAMM to mediate these activities. Immatur...
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Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.
Hyaluronan (HA) modulates key cancer cell functions through interaction with its CD44 and receptor for hyaluronic acid-mediated motility (RHAMM) receptors. HA was recently found to regulate the migration of fibrosarcoma cells in a manner specifically dependent on its size. Here, we investigated the effect of HA/RHAMM signaling on the ability of HT1080 fibrosarcoma cells to adhere onto fibronect...
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ژورنال
عنوان ژورنال: Developmental Immunology
سال: 2000
ISSN: 1044-6672
DOI: 10.1155/2000/94616